EASY
Diploma
IMPORTANT
Earn 100

Acetyl salicylic acid (aspirin) can be synthesised from salicylic acid (-Hydroxybenzoic acid). State the type of this reaction.

Important Questions on Medicinal Chemistry
EASY
Diploma
IMPORTANT
"Extra strength" aspirin tablets contain of acetyl salicylic acid. Calculate the mass of salicylic acid needed to produce a pack of extra strength aspirin tablets if the reaction yield is .

EASY
Diploma
IMPORTANT
Two examples of mild analgesics are aspirin and paracetamol (acetaminophen). Paracetamol is often used as an alternative to aspirin. State one advantage and one disadvantage of the use of paracetamol.

EASY
Diploma
IMPORTANT
Physiological effects of drugs can be significantly reduced, enhanced, or altered by other drugs or foods. The problem of drug interactions is particularly important for patients who consume excessive amounts of ethanol. State one possible adverse effect of consuming ethanol together with aspirin.

EASY
Diploma
IMPORTANT
Drugs such as fluoxetine and aspirin can be converted into salts. Identify the functional group present in each of fluoxetine and aspirin which allows them to be converted into a salt. Suggest a reagent required for each conversion.

EASY
Diploma
IMPORTANT
Explain the advantage of converting drugs such as fluoxetine and aspirin into salts.

EASY
Diploma
IMPORTANT
The discovery of penicillin by Alexander Fleming in is often given as an example of serendipity in science. Describe the chance event that led to Alexander Fleming's discovery of penicillin.

EASY
Diploma
IMPORTANT
Outline the work of Florey and Chain in developing penicillin.

EASY
Diploma
IMPORTANT
Describe what happens to bacteria when they come into contact with penicillin.
