EASY
Earn 100

All of the following are found in a prokaryotic cell, except:

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Important Questions on Molecular Basis of Inheritance

MEDIUM
The proportion of nucleotides in a given nucleic acid are adenine: 18%, guanine: 30%, cytosine: 42% and uracil: 10%. Name the nucleic acid and mention the number of strands in it.
EASY

Observe the figure and answer the questions:

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What is the function of 'A'?

MEDIUM
Draw a labelled diagram of t-RNA, the adapter molecule.
EASY
Which one of the following is not applicable to RNA?
EASY
In RNA molecule, thymine is replaced by
EASY

Observe the figure and answer the questions:

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Identify the parts A and B.

HARD

DNA Cot analysis is based upon the principles of DNA renaturation kinetics. The rate at which heat-denatured DNA sequences in solution will renature is dependent on DNA concentration, re-association temperature, cation concentration, and viscosity (usually not a factor if the DNA is free of contaminants). Upon heat-denaturation of an entire genomic DNA, the rate at which a particular sequence will re-associate in a given buffer solution is proportional to the number of times the sequence is found in the genome. Given enough time, nearly all of the DNA in a heat-denatured sample will re-associate. Highly repetitive, moderately repetitive and non-repetitive are the three types of DNA sequences found normally in all genomes giving them different levels of complexity. Typical Cot curves (see graph) were obtained for genomic DNA from three organisms (P,Q and R).

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Based on this information, select the correct option(s) from the following:

MEDIUM
Write any two chemical differences between DNA and RNA.
EASY

Identify P and Q in the following figure?

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HARD

Khorana performed experiments to decipher the codons that code for a particular amino acid. The results of these experiments using synthetic mRNAs and the corresponding polypeptide repeats that were generated are given in the table below.

Synthetic mRNAs Polypeptide(s) synthesized
CAAn Thr-Thrn and Asn-Asnn and Gln-Glnn
UUCn Ser-Sern and Leu-Leun and Phe-Phen
UACn Thr-Thrn and Leu-Leun and Tyr-Tyrn
UUACn Leu-Leu-Thr-Tyrn

Based on the results, the correct combination(s) of codons and amino acids is/are

MEDIUM
Which of the following is used for synthesis by reverse transcriptase?
MEDIUM

In biological systems, proteins (repressors and activators) control gene expression. Repressors bind to promoters and inhibit gene expression. Some promoters require activators for gene expression. These constitute a genetic circuit and are analogous to logic gates in digital electronics. A schematic diagram of a genetic circuit in a cell is shown below. Binding of IPTG to LacI activates transcription from Plac. Binding of arabinose (Ara) to AraC activates transcription from Para.

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 The correct statement(s) regarding the given genetic circuit is/are

HARD

Proteins P1 and P2  bind to each other to form a complex. This complex has a high binding affinity to a specific element on the promoter sequence of a gene X, thus transcribing it. The product of gene Xis responsible for the accumulation of red pigment in some plants. Under drought stress, another protein P3 binds to P2 and prevents its binding to P1 and the plants appear pale. The following table depicts a representation of phenotypes of wild-type and mutant  plants.

Condition/ Plant

Wild-type

Mutant-1

Mutant-2

Mutant-3

Water sufficiency

Red

Pale

Red

Pale

Drought

Pale

Pale

Red

Pale

Choose the correct statement(s).

EASY
Following is the sequence of a gene that produces peptide ' P ' and has a promoter sequence in the 5' upstream region of the sense strand and not in that of the complementary strand.
Sense strand -
5' ATGCCCTGCACTGCAGGGCAT 3'
Complementary strand -
3'TACGGGACGTCACGTCCCGTA 5'
If Adenine is replaced with Thymine, and Guanine is replaced with Cytosine and vice-versa in both the DNA strands, then
HARD
Describe the clover leaf model of tRNA.
EASY
Which one of the following processes in E. coli does not directly involve RNA?
EASY
Which of the following statements is correct?

a. rRNA is the most abundant RNA.
b. Ribosomes are composed of approximately 80% rRNA and 20% ribosomal proteins.
c. rRNA is a type of coding RNA.