EASY
Earn 100

Define therapeutic window.

Important Questions on Medicinal Chemistry

MEDIUM
Chemistry>Organic Chemistry>Medicinal Chemistry>Introduction to Medicinal Chemistry
Define therapeutic index (TI).
EASY
Chemistry>Organic Chemistry>Medicinal Chemistry>Introduction to Medicinal Chemistry
List the two other methods, which can be used to inject drugs into the body.
EASY
Chemistry>Organic Chemistry>Medicinal Chemistry>Introduction to Medicinal Chemistry

Drugs can be prescribed for treating various diseases and assisting in healing the human body. However, any drug presents potential risks. The properties of three drugs are summarised in the below table:

Drug Physiological effect Side-effects Therapeutic window
A High Severe Medium
B Moderate Moderate Narrow
C Low Minimal Wide

Suggest which drug (A, B, or C) could be used only in a medical emergency?

EASY
Chemistry>Organic Chemistry>Medicinal Chemistry>Introduction to Medicinal Chemistry
Describe the double-blind test in the clinical trial.
EASY
Chemistry>Organic Chemistry>Medicinal Chemistry>Introduction to Medicinal Chemistry
The effectiveness of a drug depends on the method of administration. One method of injecting drugs into the body results in the drug having a very rapid effect. State the method and explain its rapid action.
EASY
Chemistry>Organic Chemistry>Medicinal Chemistry>Introduction to Medicinal Chemistry
Describe the placebo effect and state its importance in drug development.
EASY
Chemistry>Organic Chemistry>Medicinal Chemistry>Introduction to Medicinal Chemistry
The therapeutic action of a placebo, known as the _____.
EASY
Chemistry>Organic Chemistry>Medicinal Chemistry>Introduction to Medicinal Chemistry
Medicines and drugs alter the physiological state of the body including consciousness and coordination. State one other effect of medicines and drugs on the body.
EASY
Chemistry>Organic Chemistry>Medicinal Chemistry>Introduction to Medicinal Chemistry
Identify the method of administration used to treat respiratory diseases such as asthma.
EASY
Chemistry>Organic Chemistry>Medicinal Chemistry>Introduction to Medicinal Chemistry

Drugs can be prescribed for treating various diseases and assisting in healing the human body. However, any drug presents potential risks. The properties of three drugs are summarised in the below table:

Drug Physiological effect Side-effects Therapeutic window
A High Severe Medium
B Moderate Moderate Narrow
C Low Minimal Wide

Suggest which drug (A, B, or C) could be considered safe enough to be taken by patients without supervision?

EASY
Chemistry>Organic Chemistry>Medicinal Chemistry>Introduction to Medicinal Chemistry
Define Placebo effect.
EASY
Chemistry>Organic Chemistry>Medicinal Chemistry>Introduction to Medicinal Chemistry
_____ is measured as the dose that causes toxicity (an unacceptable adverse effect) in 50% of patients.
EASY
Chemistry>Organic Chemistry>Medicinal Chemistry>Introduction to Medicinal Chemistry
Drugs are most commonly taken orally. List three methods, other than orally, that can be used for the administration of a drug.
EASY
Chemistry>Organic Chemistry>Medicinal Chemistry>Introduction to Medicinal Chemistry
Define toxic dose of a drug.
EASY
Chemistry>Organic Chemistry>Medicinal Chemistry>Introduction to Medicinal Chemistry
Drugs are most commonly taken orally. State one advantage and one disadvantage of this.
EASY
Chemistry>Organic Chemistry>Medicinal Chemistry>Introduction to Medicinal Chemistry
Medicines and drugs are natural or synthetic substances used for their effects on the body. List two general effects of medicines and drugs on the functioning of the body.
MEDIUM
Chemistry>Organic Chemistry>Medicinal Chemistry>Introduction to Medicinal Chemistry

Represent the union of two sets by Venn diagram for each of the following.

X={x | x is a prime number between 80 and 100}

Y={y | y is an odd number between 90 and 100}

EASY
Chemistry>Organic Chemistry>Medicinal Chemistry>Introduction to Medicinal Chemistry
Explain the meaning of the term drug tolerance.
EASY
Chemistry>Organic Chemistry>Medicinal Chemistry>Introduction to Medicinal Chemistry

Drugs can be prescribed for treating various diseases and assisting in healing the human body. However, any drug presents potential risks. The properties of three drugs are summarised in the below table:

Drug Physiological effect Side-effects Therapeutic window
A High Severe Medium
B Moderate Moderate Narrow
C Low Minimal Wide

Suggest which drug (A, B, or C) could be administered only by qualified staff?

EASY
Chemistry>Organic Chemistry>Medicinal Chemistry>Introduction to Medicinal Chemistry
Explain the significance of the therapeutic index (TI)?