Drugs can be prescribed for treating various diseases and assisting in healing the human body. However, any drug presents potential risks. The properties of three drugs are summarised in the below table: Drug Physiological effect Side-effects Therapeutic window A High Severe Medium B Moderate Moderate Narrow C Low Minimal Wide Suggest which drug (A, B, or C) could be considered safe enough to be taken by patients without supervision?

The drug with low physiological effect, minimal side effects, and wide therapeutic window could be considered safe hence, according to the given table, the drug C can be taken by the patients without supervision. Drug Physiological effect Side-effects Therapeutic window A High Severe Medium B Moderate Moderate Narrow C Low Minimal Wide

Drugs can be prescribed for treating various diseases and assisting in healing the human body. However, any drug presents potential risks. The properties of three drugs are summarised in the below table: Drug Physiological effect Side-effects Therapeutic window A High Severe Medium B Moderate Moderate Narrow C Low Minimal Wide Suggest which drug (A, B, or C) could be administered only by qualified staff?

The drug with high (or moderate) physiological effect, severe (or moderate) side effects, and medium (narrow) therapeutic window could be considered unsafe hence, according to the given table, the drug A and B could be administered only by the qualified staff. Drug Physiological effect Side-effects Therapeutic window A High Severe Medium B Moderate Moderate Narrow C Low Minimal Wide

Drugs can be prescribed for treating various diseases and assisting in healing the human body. However, any drug presents potential risks. The properties of three drugs are summarised in the below table: Drug Physiological effect Side-effects Therapeutic window A High Severe Medium B Moderate Moderate Narrow C Low Minimal Wide Suggest which drug (A, B, or C) could be used only in a medical emergency?

The drug with high physiological effect, severe side effects, and medium therapeutic window could be considered unsafe hence, according to the given table, the drug A could be used only in a medical emergency. Drug Physiological effect Side-effects Therapeutic window A High Severe Medium B Moderate Moderate Narrow C Low Minimal Wide

Explain the meanings of the terms lethal dose LD50 toxic dose TD50 and effective dose ED50

EASY

Diploma

IMPORTANT

Oxford IB Diploma Programme Chemistry Course Companion>Chapter 25 - Medicinal Chemistry>Questions>Q 1

Explain how lethal dose, toxic dose and effective dose can be determined in animal and human studies?

EASY

Diploma

IMPORTANT

Oxford IB Diploma Programme Chemistry Course Companion>Chapter 25 - Medicinal Chemistry>Questions>Q 2

Medicines and drugs alter the physiological state of the body including consciousness and coordination. State one other effect of medicines and drugs on the body.

EASY

Diploma

IMPORTANT

Oxford IB Diploma Programme Chemistry Course Companion>Chapter 25 - Medicinal Chemistry>Questions>Q 2

Explain the meaning of the term, therapeutic window.

EASY

Diploma

IMPORTANT

Oxford IB Diploma Programme Chemistry Course Companion>Chapter 25 - Medicinal Chemistry>Questions>Q 2

Explain the meaning of the term drug tolerance.

EASY

Diploma

IMPORTANT

Oxford IB Diploma Programme Chemistry Course Companion>Chapter 25 - Medicinal Chemistry>Questions>Q 3

Describe how computers can be used to predict how changes to the structure of a drug might affect its activity?

EASY

Diploma

IMPORTANT

Oxford IB Diploma Programme Chemistry Course Companion>Chapter 25 - Medicinal Chemistry>Questions>Q 4

Drugs can be prescribed for treating various diseases and assisting in healing the human body. However, any drug presents potential risks. The properties of three drugs are summarised in the below table:

Drug	Physiological effect	Side-effects	Therapeutic window
A	High	Severe	Medium
B	Moderate	Moderate	Narrow
C	Low	Minimal	Wide

Suggest which drug (A, B, or C) could be considered safe enough to be taken by patients without supervision?

EASY

Diploma

IMPORTANT

Oxford IB Diploma Programme Chemistry Course Companion>Chapter 25 - Medicinal Chemistry>Questions>Q 4

Drugs can be prescribed for treating various diseases and assisting in healing the human body. However, any drug presents potential risks. The properties of three drugs are summarised in the below table:

Drug	Physiological effect	Side-effects	Therapeutic window
A	High	Severe	Medium
B	Moderate	Moderate	Narrow
C	Low	Minimal	Wide

Suggest which drug (A, B, or C) could be administered only by qualified staff?

EASY

Diploma

IMPORTANT

Oxford IB Diploma Programme Chemistry Course Companion>Chapter 25 - Medicinal Chemistry>Questions>Q 4

Drugs can be prescribed for treating various diseases and assisting in healing the human body. However, any drug presents potential risks. The properties of three drugs are summarised in the below table:

Drug	Physiological effect	Side-effects	Therapeutic window
A	High	Severe	Medium
B	Moderate	Moderate	Narrow
C	Low	Minimal	Wide

Suggest which drug (A, B, or C) could be used only in a medical emergency?

Explain the meanings of the terms lethal dose ( ${LD}_{50}$ ), toxic dose ( ${TD}_{50}$ ) and effective dose ( ${ED}_{50}$ ).

Important Questions on Medicinal Chemistry

Learn and Prepare for any exam you want !

Explain the meanings of the terms lethal dose (LD50), toxic dose (TD50) and effective dose (ED50).

Important Questions on Medicinal Chemistry

Learn and Prepare for any exam you want !

Explain the meanings of the terms lethal dose ( ${LD}_{50}$ ), toxic dose ( ${TD}_{50}$ ) and effective dose ( ${ED}_{50}$ ).