HARD
AS and A Level
IMPORTANT
Earn 100
Explain why it is easier to devise a gene therapy for a condition caused by a recessive allele than for one caused by a dominant allele.
Important Questions on Genetic Technology
HARD
AS and A Level
IMPORTANT
Explain the advantages and disadvantages of genetic screening.
HARD
AS and A Level
IMPORTANT
The Crispr/Cas9 system is a gene-editing technique that has been used extensively since being introduced in 2012. The diagram shows how Cas9 functions.
Name the molecule labelled A and explain its role in gene editing.
HARD
AS and A Level
IMPORTANT
Explain how Crispr/Cas9 can be used to correct the function of a faulty allele.
HARD
AS and A Level
IMPORTANT
In 2016, it was reported that scientists had removed the protein PD-1 from T-lymphocytes in a human patient. Outline the importance of T-lymphocytes.
HARD
AS and A Level
IMPORTANT
In 2016, it was reported that scientists had removed the protein PD-1 from T-lymphocytes in a human patient. Explain how Crispr/Cas9 can be used to remove a protein from specialised cells, such as T-lymphocytes.
HARD
AS and A Level
IMPORTANT
Explain why Crispr/Cas9 is likely to be used to treat people with blood disorders rather than disorders of the nervous and muscular systems.
HARD
AS and A Level
IMPORTANT
Suggest the advantages of using gene editing using Crispr/Cas9 over other methods of gene technology, such as gene therapy using viruses.
HARD
AS and A Level
IMPORTANT
The graph shows the changes in temperature in a PCR machine during two cycles. Explain why a high temperature is required for stage 1.
