How many such pairs of letters are there in the word REFRESHING, each of which has as many letters between them (in both forward and backward directions) in the word as they have in the English alphabet?

If in the word ISOLATE, all the consonants are replaced by the previous letter in the alphabet and all vowels are replaced by the next letter and then all the letters are arranged alphabetically, which letter will be third from the right end?

If in the number 38564927, first all the even digits are arranged in ascending order and then all the odd digits are arranged in ascending order, which digit will be fourth from the right end?

What will come in place of question mark(?) in the below question?

$\frac{{?}^{1.8}}{32}=\frac{16}{{?}^{1.2}}$