Match the following:

	Karyotype of Drosophila		Sex
A)	$\mathrm{AA}+\mathrm{XX}$	$\mathrm{I})$	Metafemale
B)	$\mathrm{AA}+\mathrm{XO}$	$\mathrm{II})$	Female
C)	$\mathrm{AA}+\mathrm{XXX}$	$\mathrm{III})$	Intersex
D)	$\mathrm{AAA} + \mathrm{XXY}$	$\mathrm{IV})$	Metamale
		$\mathrm{V})$	Male

The correct match is

In which of the organism, the following type of sex determination is possible

Statement I : All the three types of allosomal genes - $\mathrm{X}$ linked, $\mathrm{Y}$ linked and $\mathrm{XY}$ linked are present only in male human being.
Statement II : Only $\mathrm{X}$ linked and not $\mathrm{XY}$ linked genes are present in female human being.

The correct option among the following is

Statement (S): The heterozygous individuals for sickle-cell anaemia $\left({\mathrm{Hb}}^{\mathrm{A}}{\mathrm{Hb}}^{\mathrm{S}}\right)$ express disease phenotype and also carriers of the disease.

Reason (R): ${\mathrm{Hb}}^{\mathrm{A}}{\mathrm{Hb}}^{\mathrm{S}}$ genotype individuals are resistant to severe effects of malaria.

The correct answer is