The alternative names of intermedin are melanocyte-stimulating hormones (MSH) and melanotropins. Melanocyte Stimulating Hormone (MSH) are a family of peptide hormones and neuropeptides that stimulate the production and release of melanin. This hormone is released from the pars intermedia of the pituitary gland, which is the intermediate lobe of the pituitary gland.

Goitre is a condition in which the thyroid gland swells, resulting in the appearance of a lump in the front of the neck. Iodine is necessary for the synthesis of thyroid hormones. The deficiency of iodine in the diet causes low secretion of thyroid hormones from the gland. Due to low thyroid hormone, the gland is stimulated by a hormone from the adenohypophysis called TSH to produce more hormone that leads to swelling in the thyroid gland, called goitre. Symptoms of goitre are coughing, difficulty in swallowing, low BMR, low metabolism, etc.