Match the disease given in Column I with the principal causal organism in Column II and choose the correct combination. Column I Column II P AIDS i HBV Q Syphilis i i Neisseria sp. R Viral hepatitis i i i Treponema sp. ( S ) Gonorrhoea i v HIV

P - i v , Q - i i i , R - i , S - i i

P - i v , Q - i i , R - i , S - i i i

P - i , Q - i i , R - i v , S - i i i

P - i , Q - i i , R - i i , S - i i i

Observe the figure and answer the question that follows. Give two symptoms and mode of transmission of the disease caused by this virus.

The virus is a nucleic acid either RNA or DNA surrounded by a coating called a capsid. The structure of HIV is shown in the figure. AIDS is a disorder caused by Human Immunodeficiency Virus (HIV). Two symptoms of AIDS are: 1. The person experiences fever, diarrhoea and weight loss during this period. 2. The immunity decreases due to the decrease in the number of T-cells. Two modes of transmission of AIDS are: 1. Sexual contact with infected person. 2. From infected mother to her child through placenta.

Match Column I with Column II and select the correct option from the given codes. Column I Column II ( a ) Syphilis ( i ) Human papilloma virus ( b ) Chancroid ( i i ) Haemophilus ducreyi ( c ) AIDS ( i i i ) Treponema pallidum ( d ) Genital warts ( i v ) HIV

a b c d ( i i i ) ( i i ) ( i v ) ( i )

a b c d ( i i ) ( i ) ( i i i ) ( i v )

a b c d ( i v ) ( i i ) ( i ) ( i i i )

a b c d ( i ) ( i v ) ( i i i ) ( i i )

Observe the figure and answer the question that follows. Name the disease caused by this virus.

The structure of HIV is shown in the figure. AIDS (Acquired immunodeficiency syndrome) is a disorder caused by Human Immunodeficiency Virus (HIV). This virus is pathogenic to human beings as it damages the immune system of the human body resulting in loss of natural defence. AIDS is usually the last stage of HIV infection; a stage where the body can no longer defend itself and thus sires various diseases.

Observe the figure and answer the question that follows. What is shown in figure?

The virus is a nucleic acid either RNA or DNA surrounded by a coating called a capsid. The structure of HIV is shown in the figure. AIDS is a disorder caused by Human Immunodeficiency Virus (HIV). This virus is pathogenic to human beings as it damages the immune system of the human body resulting in loss of natural defence. This virus has a long incubation period before it starts to attack the immune system.

EASY

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Paclitaxel (Taxol) is an anticancer drug that can be extracted from the bark of Pacific yew tree (Taxus brevifolia) or produced semi-synthetically using extracts from the leaves of European yew trees (Taxus baccata). Since $1994$ the total synthesis of Taxol has been reported by several research groups in different countries. Suggest why total synthesis is not used for producing Taxol on an industrial scale?

Important Questions on Medicinal Chemistry

EASY

Chemistry>Organic Chemistry>Medicinal Chemistry>Taxol

Which of the following is correct regarding AIDS causative agent HIV?

EASY

Chemistry>Organic Chemistry>Medicinal Chemistry>Taxol

Match the disease given in Column I with the principal causal organism in Column II and choose the correct combination.

Column I	Column II
$(P)$ $AIDS$	$(i)$ $HBV$
$(Q)$ Syphilis	$(i i)$ Neisseria sp.
$(R)$ Viral hepatitis	$(i i i)$ Treponema sp.
$(S)$ Gonorrhoea	$(i v)$ $HIV$