Match the following: Disorder Reason A) Thalassemia B) Haemophilia C) Sickle cell anaemia D) Alkaptonuria I) Point mutation II) Autosomal recessive metabolic disorder III) Abnormal haemoglobin IV) Non-disjunction of chromosomes V) Sex-linked recessive disorder The correct match is:

A = III , B = V , C = I , D = II

A = III , B = IV , C = I , D = II

A = II , B = I , C = V , D = III

A = IV , B = III , C = II , D = I

Match the following: Disorder Reason A) Thalassemia B) Haemophilia C) Sickle cell anaemia D) Alkaptonuria I) Point mutation II) Autosomal recessive metabolic disorder III) Abnormal haemoglobin IV) Non-disjunction of chromosomes V) Sex-linked recessive disorder The correct match is:

A = III , B = V , C = I , D = II

A = III , B = IV , C = I , D = II

A = II , B = I , C = V , D = III

A = IV , B = III , C = II , D = I

Assertion (A) : If the allele produces a less functional enzyme or non-functional enzyme the phenotype may be affected. Reason (R) : The phenotype trait will not be dependent on the functioning of the unmodified allele. The correct option among the following is:

(A) is true, (R) is true and (R) is the correct explanation for (A)

(A) is true, (R) is true but (R) is not the correct explanation for (A)

Assertion (A): In human beings, the sex of the offspring depends on the type of sperm that fertilizes the ovum Reason (R): Human males are heterogametic The correct option among the following is

(A) is true, (R) is true and (R) is the correct explanation for (A)

(A) is true, (R) is true, but (R) is not the correct explanation for (A)

E M B I B E

EMBIBE CHAPTER WISE PREVIOUS YEAR PAPERS FOR BIOLOGY>Chapter 19 - Principles of Inheritance and Variation>TS EAMCET Medical 2019 (8-May Shift-2)>Q 21

EASY

TS EAMCET

IMPORTANT

Earn 100

Statement (S): The heterozygous individuals for sickle-cell anaemia $({Hb}^{A} {Hb}^{S})$ express disease phenotype and also carriers of the disease.

Reason (R): ${Hb}^{A} {Hb}^{S}$ genotype individuals are resistant to severe effects of malaria.

The correct answer is

50% studentsanswered this correctly

Important Questions on Principles of Inheritance and Variation

EASY

TS EAMCET

IMPORTANT

EMBIBE CHAPTER WISE PREVIOUS YEAR PAPERS FOR BIOLOGY>Chapter 19 - Principles of Inheritance and Variation>TS EAMCET Medical 2018 (02 May Shift-1)>Q 22

A change of single base pair in the gene for beta globin chain (in human haemoglobin) that results in the change of amino acid residue glutamine to valine which is due to

MEDIUM

TS EAMCET

IMPORTANT

EMBIBE CHAPTER WISE PREVIOUS YEAR PAPERS FOR BIOLOGY>Chapter 19 - Principles of Inheritance and Variation>TS EAMCET Medical 2021 (9-Aug Shift-1)>Q 23

Match the following:

Disorder	Reason
A) Thalassemia B) Haemophilia C) Sickle cell anaemia D) Alkaptonuria	I) Point mutation II) Autosomal recessive metabolic disorder III) Abnormal haemoglobin IV) Non-disjunction of chromosomes V) Sex-linked recessive disorder

The correct match is:

EASY

TS EAMCET

IMPORTANT

EMBIBE CHAPTER WISE PREVIOUS YEAR PAPERS FOR BIOLOGY>Chapter 19 - Principles of Inheritance and Variation>TS EAMCET - 9 August 2021 Shift 2>Q 24

A woman (whose father is haemophilic and mother is homozygous normal) married a normal man and had two sons and two daughters. What are the chances of their sons being haemophilic?

MEDIUM

TS EAMCET

IMPORTANT

EMBIBE CHAPTER WISE PREVIOUS YEAR PAPERS FOR BIOLOGY>Chapter 19 - Principles of Inheritance and Variation>TS EAMCET - 10 August 2021 Shift 1>Q 25

Karyotype of Klinefelter syndrome is

HARD

TS EAMCET

IMPORTANT

EMBIBE CHAPTER WISE PREVIOUS YEAR PAPERS FOR BIOLOGY>Chapter 19 - Principles of Inheritance and Variation>TS EAMCET 2020 (28-Sep Shift-1)>Q 26

Match the following lists:

	List $I$		List $II$
A)	Change in single base pair of DNA	$I)$	Recombination
B)	Deletions of base pairs of DNA	$II)$	Genetic map
C)	Generation of non-parental gene combination	$III)$	Point mutations
D)	The frequency of recombination between gene pairs on the same chromosome	$IV)$	Frame-shift mutations