HARD
Diploma
IMPORTANT
Earn 100

The oxygen-binding capacity of hemoglobin is affected by pH. The saturation curve of hemoglobin at normal physiological pH (7.4) is given in figure below.

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Sketch the saturation curve of hemoglobin at pH = 7.2 .

Important Questions on Biochemistry

HARD
Diploma
IMPORTANT

Explain, in terms of enzyme inhibition, the effects of protons and carbon monoxide on the saturation curve of hemoglobin.

MEDIUM
Diploma
IMPORTANT

Experiments show that our appreciation of food is based on interactions between our senses. Discuss how the different senses interact in giving us empirical knowledge about the world.

EASY
Diploma
IMPORTANT
Amino acids can exist in D and L forms. Describe how the D form of alanine, H2NCH(CH3)COOH, differs in its physical properties from the L form.
EASY
Diploma
IMPORTANT
Explain the D and L convention for describing amino acids and draw the D form of alanine to show clearly its three-dimensional structure.
EASY
Diploma
IMPORTANT
Explain how the “CORN” rule can be used to identify an enantiomer of alanine as either D- or L-alanine.
EASY
Diploma
IMPORTANT
Identify, by marking with asterisk (*) symbols, all chiral carbon atoms in the molecules of leucine, isoleucine, valine, proline, and threonine (sub-topic B.2, table 1). Remember that some amino acids contain more than one chiral centre.
EASY
Diploma
IMPORTANT
The reason why only L-enantiomers of 2-amino acids are found in proteins remains a mystery. It is possible that this selection was made arbitrarily and then fixed firmly in evolutionary history. Discuss the role of random events in evolution.
EASY
Diploma
IMPORTANT
The reason why only L-enantiomers of 2-amino acids are found in proteins remains a mystery. It is possible that this selection was made arbitrarily and then fixed firmly in evolutionary history. A photosynthesizing organism based on D-amino acids could potentially be created artificially. Discuss possible environmental implications of such an experiment.