MEDIUM
AS and A Level
IMPORTANT
Earn 100
The table shows enzymes that are used in gene technology. Complete the table to show the role of each enzyme.
Enzyme
Role
DNA ligase
DNA polymerase
restriction enzyme
reverse transcriptase
Cas9
Important Questions on Genetic Technology
HARD
AS and A Level
IMPORTANT
Explain why it is easier to devise a gene therapy for a condition caused by a recessive allele than for one caused by a dominant allele.
HARD
AS and A Level
IMPORTANT
Explain the advantages and disadvantages of genetic screening.
HARD
AS and A Level
IMPORTANT
The Crispr/Cas9 system is a gene-editing technique that has been used extensively since being introduced in 2012. The diagram shows how Cas9 functions.
Name the molecule labelled A and explain its role in gene editing.
HARD
AS and A Level
IMPORTANT
Explain how Crispr/Cas9 can be used to correct the function of a faulty allele.
HARD
AS and A Level
IMPORTANT
In 2016, it was reported that scientists had removed the protein PD-1 from T-lymphocytes in a human patient. Outline the importance of T-lymphocytes.
HARD
AS and A Level
IMPORTANT
In 2016, it was reported that scientists had removed the protein PD-1 from T-lymphocytes in a human patient. Explain how Crispr/Cas9 can be used to remove a protein from specialised cells, such as T-lymphocytes.
HARD
AS and A Level
IMPORTANT
Explain why Crispr/Cas9 is likely to be used to treat people with blood disorders rather than disorders of the nervous and muscular systems.
HARD
AS and A Level
IMPORTANT
Suggest the advantages of using gene editing using Crispr/Cas9 over other methods of gene technology, such as gene therapy using viruses.
