MEDIUM
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What is drug design?

Important Questions on Medicinal Chemistry

EASY
Chemistry>Organic Chemistry>Medicinal Chemistry>Drug Action and Development of New Drugs
Describe how computers can be used to predict how changes to the structure of a drug might affect its activity?
HARD
Chemistry>Organic Chemistry>Medicinal Chemistry>Drug Action and Development of New Drugs
Which type of inhibitor binds at the active site?
HARD
Chemistry>Organic Chemistry>Medicinal Chemistry>Drug Action and Development of New Drugs
What are enzyme inhibitors? Classify them on the basis of their mode of attachments on the active site of enzymes. With the help of diagrams explain how do inhibitors inhibit the enzymatic activity?
MEDIUM
Chemistry>Organic Chemistry>Medicinal Chemistry>Drug Action and Development of New Drugs
Which of the following statements is not true about enzyme inhibitors?
EASY
Chemistry>Organic Chemistry>Medicinal Chemistry>Drug Action and Development of New Drugs
The drugs which interact with target biomolecules are called _____.
HARD
Chemistry>Organic Chemistry>Medicinal Chemistry>Drug Action and Development of New Drugs
Drugs that bind to the receptor site and inhibit its natural function are called
EASY
Chemistry>Organic Chemistry>Medicinal Chemistry>Drug Action and Development of New Drugs
Describe briefly how pharmaceutical drugs can interact with receptors and enzymes.
MEDIUM
Chemistry>Organic Chemistry>Medicinal Chemistry>Drug Action and Development of New Drugs
Which of the following statements are incorrect about receptor proteins?
HARD
Chemistry>Organic Chemistry>Medicinal Chemistry>Drug Action and Development of New Drugs
Penicillin acts as an inhibitor.
EASY
Chemistry>Organic Chemistry>Medicinal Chemistry>Drug Action and Development of New Drugs

Among the following which drugs mimic natural messengers ?

HARD
Chemistry>Organic Chemistry>Medicinal Chemistry>Drug Action and Development of New Drugs
What are antagonists and agonists?
EASY
Chemistry>Organic Chemistry>Medicinal Chemistry>Drug Action and Development of New Drugs
The decomposition of hydrogen peroxide can be slowed by the addition of a small amount of acetamide. The latter acts as a/an ______
MEDIUM
Chemistry>Organic Chemistry>Medicinal Chemistry>Drug Action and Development of New Drugs
Which of the following statements are incorrect about receptor proteins?
EASY
Chemistry>Organic Chemistry>Medicinal Chemistry>Drug Action and Development of New Drugs
Explain how lethal dose, toxic dose and effective dose can be determined in animal and human studies?
EASY
Chemistry>Organic Chemistry>Medicinal Chemistry>Drug Action and Development of New Drugs
Why are certain drugs called enzyme inhibitors?
HARD
Chemistry>Organic Chemistry>Medicinal Chemistry>Drug Action and Development of New Drugs
What is true for a competitive inhibitor?
MEDIUM
Chemistry>Organic Chemistry>Medicinal Chemistry>Drug Action and Development of New Drugs
An inhibitor is described as:
MEDIUM
Chemistry>Organic Chemistry>Medicinal Chemistry>Drug Action and Development of New Drugs
Which of the following statements is not true about enzyme inhibitors?
MEDIUM
Chemistry>Organic Chemistry>Medicinal Chemistry>Drug Action and Development of New Drugs

Match the class of compounds given in Column I with their functions given in Column II.

Column I  Column II
(i) Antagonists (a) Communicate message between two neurons and that  between neurons to muscles
(ii) Agonists (b) Bind to the receptor site and inhibit its natural function
(iii) Chemical messenger (c) Crucial to body’s communication process
(iv) Inhibitors (d) Mimic the natural messenger
(v) Receptors (e) Inhibit activities of enzymes.

 

 

HARD
Chemistry>Organic Chemistry>Medicinal Chemistry>Drug Action and Development of New Drugs
What are enzyme inhibitors?