A novel species with double-stranded genetic material consists of 5 bases namely P , Q , R , S , T , with percentage given below. P Q R S T Percentage 22 28 22 12 16 Based on the above information, which one of the following inferences is not supported by the observations?

S base pairs with T and Q base pairs with R

S base pairs with Q and T base pairs with Q

P base pairs with R and S base pairs with Q

P base pairs with R and T base pairs with Q

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What is the length of human DNA containing $6.6 \times 10^{9} b p$ ?

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Important Questions on Molecular Basis of inheritance

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Biology>Molecular Biology>Molecular Basis of inheritance>Structure of DNA and DNA Packaging

DNA molecule which has the highest number of hydrogen bonds

HARD

Biology>Molecular Biology>Molecular Basis of inheritance>Structure of DNA and DNA Packaging

Assertion $(A) :$ Between $DNA$ and $RNA$ , $DNA$ is a better genetic material.

Reason $(R) :$ $2^{'}$ $- OH$ group present in every nucleotide in $RNA$ is a reactive group and make $RNA$ labile and easily degradable.

The correct answer is:

HARD

Biology>Molecular Biology>Molecular Basis of inheritance>Structure of DNA and DNA Packaging

DNA molecule has length of $476 \overset{\circ}{A}$ with $20 %$ guanosine. Choose the correct features of $DNA$

$I)$ $56 CTP$
$II)$ $336$ Hydrogen bonds
$III)$ Total $150$ nucleotides
$IV)$ $84 TTP$

HARD

Biology>Molecular Biology>Molecular Basis of inheritance>Structure of DNA and DNA Packaging

A newly discovered organism possesses a genetic material with a new base composition consisting of the sugar and phosphate backbone as found in existing natural

DNA

. The five novel bases in this genetic material-namely,

P, Q, R, S, T

are heterocyclic structures with

1, 1, 2, 2

and

3

rings, respectively. Assuming the new

DNA

forms a double helix of uniform width, which one of the following would be the most appropriate base pairing?

EASY

Biology>Molecular Biology>Molecular Basis of inheritance>Structure of DNA and DNA Packaging

If a double-stranded

DNA

has

15 %

cytosine, what is the

%

of adenine in the

DNA

?

HARD

Biology>Molecular Biology>Molecular Basis of inheritance>Structure of DNA and DNA Packaging

A novel species with double-stranded genetic material consists of

5

bases namely

P, Q, R, S, T,

with percentage given below.

	$P$	$Q$	$R$	$S$	$T$
Percentage	$22$	$28$	$22$	$12$	$16$

Based on the above information, which one of the following inferences is not supported by the observations?

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Biology>Molecular Biology>Molecular Basis of inheritance>Structure of DNA and DNA Packaging

Choose the correct statement

I)

Secondary metabolites do not have identifiable physiological processes in plants, fungal and microbial cells

I I)

Bio macromolecules are acid insoluble organic compounds with mol wt more than

10, 000

daltons

I I I)

Uridylic acid and cytidylic acids are derived from uracil and cytosine by esterification

I V)

Lecithin and lectin are phospholipids found in cell membrane

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Biology>Molecular Biology>Molecular Basis of inheritance>Structure of DNA and DNA Packaging

What is the difference between a nucleoside and a nucleotide?

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Biology>Molecular Biology>Molecular Basis of inheritance>Structure of DNA and DNA Packaging

The sequences of four DNA molecules are given. Which one of these DNA molecules will have the highest melting temperature

(T_{m})

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Biology>Molecular Biology>Molecular Basis of inheritance>Structure of DNA and DNA Packaging

Watson and Crick model of DNA is

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Biology>Molecular Biology>Molecular Basis of inheritance>Structure of DNA and DNA Packaging

Match the following lists:

	List $I$		List $II$
A)	X-ray diffraction data	$I)$	Chargaff
B)	DNA double stranded	$II)$	Meischer
C)	DNA double helix	$III)$	Wilkins
D)	DNA as an acidic substance	$IV)$	Watson $&$ Crick

The correct match is

EASY

Biology>Molecular Biology>Molecular Basis of inheritance>Structure of DNA and DNA Packaging

If a dsDNA has 20% adenine, what would be its cytosine content?

HARD

Biology>Molecular Biology>Molecular Basis of inheritance>Structure of DNA and DNA Packaging

A bacteriophage

T 2

particle contains within its head a double-stranded

B

-from DNA of molecular weight

1.2 \times 10^{8} Da .

Assume that the head of a

T 2

Phage particle is of

210 nm

in length and the average molecular weight of a nucleotide is

330 Da .

The length of the

T 2

genome is in the range of

HARD

Biology>Molecular Biology>Molecular Basis of inheritance>Structure of DNA and DNA Packaging

The average energy of each hydrogen bond in

A - T

pair is

x kcal

{mol}^{- 1}

and that in

G - C

pair is

y {kcalmol}^{- 1}

. Assuming that no other interaction exists between the nucleotides, the approximate energy required in

{kcalmol}^{- 1}

to split the following double stranded

DNA

into two single strands is
Question Image

[Each dashed line may represent more than one hydrogen bond between the base pairs]

EASY

Biology>Molecular Biology>Molecular Basis of inheritance>Structure of DNA and DNA Packaging

In a segment of DNA with

10

base pairs, the number of sugar molecules are __________.

EASY

Biology>Molecular Biology>Molecular Basis of inheritance>Structure of DNA and DNA Packaging

Assertion (

A

): Purine always comes opposite to a pyrimidine.
Reason (R): Appropriate uniform distance is maintained between the two strands of the

DNA

helix.

EASY

Biology>Molecular Biology>Molecular Basis of inheritance>Structure of DNA and DNA Packaging

If Adenine makes

30 %

of the DNA molecule, what will be the percentage of Thymine, Guanine and Cytosine in it?

EASY

Biology>Molecular Biology>Molecular Basis of inheritance>Structure of DNA and DNA Packaging

Which one of the following is the complementary sequence for the DNA with

5^{'} - C G T A C T A - 3^{'}

EASY

Biology>Molecular Biology>Molecular Basis of inheritance>Structure of DNA and DNA Packaging

Considering the average molecular mass of a base to be 500 Da, what is the molecular mass of double stranded DNA of 10 base pairs?

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Biology>Molecular Biology>Molecular Basis of inheritance>Structure of DNA and DNA Packaging

In sea urchin DNA, which is double-stranded,

17 %

of the bases were shown to be cytosine. What are the percentages of other three bases expected to be present in this DNA?

What is the length of human DNA containing 6.6×109 bp ?

Important Questions on Molecular Basis of inheritance

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What is the length of human DNA containing $6.6 \times 10^{9} b p$ ?