MEDIUM
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What is the pH range of concentration of acid produced in the stomach?

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Important Questions on Medicinal Chemistry

EASY
Which of the following is used as antacid in medicine?
EASY

Match the digestive glands given in Column - I with their respective enzymes given in Column — II and choose the correct combination from the given options,

  Column I   Column II
(1) Pancreas (p) Pepsin
(2) Gastric glands (q) Enterokinase
(3) Small intestine (r) Ptyalin
(4) Salivary glands (s) Trypsin

Choose the correct option:- 

EASY
Amongst the following compounds, which one is an antacid?
MEDIUM
Which of the following compounds is not an antacid?
EASY
An enzyme with optimal activity at pH 2.0 and 37°C is most likely to be:
EASY
Which one of the following chemicals is responsible for the production of HCl in the stomach leading to irritation and pain?
HARD
Among the following, an example of antacid is
MEDIUM
Identify the compound which does NOT act as an antacid.
EASY
While antacids and antiallergic drugs interfere with the function of histamines, why do these not interfere with the function of each other?
HARD

100 cm3 of  0.100 mol dm-3 solutions of sodium carbonate and 200 cm3 of 0.100 mol dm-3 sodium hydrogencarbonate are mixed together to prepare 300 cm3 of a buffer solution with pH 10.0. The pKa2for carbonic acid is 10.3. This buffer solution is mixed with 50.0 cm3 of 10.0 mmol dm-3 hydrochloric acid. Calculate the pH of the final solution. Assume that the volume of the final solution is equal to the sum of volumes of initial solutions.

MEDIUM
Calculate the volumes, in cm3 of 0.100 mol dm-3 solutions of sodium carbonate and sodium hydrogencarbonate that need to be mixed together to prepare 300 cm3 of a buffer solution with pH 10.0. The pKa2for carbonic acid is 10.3. Assume that the volume of the final solution is equal to the sum of volumes of initial solutions.
HARD
What causes the problem of acidity? What is its effect on the body?
EASY
How does pepsinogen change into its active form?
EASY
The process of digestion involves, secretion of sulphuric acid by the stomach lining.
HARD
Give reasons.
Food becomes acidic in the stomach. 
MEDIUM
Explain the role of histamine in the control of acidity of gastric juice at cellular level.
MEDIUM
Explain the role of the following in the process of digestion in the human body.  
Gastric juices
HARD
Which one of the following pairs of the kind of cells and their secretion are correctly matched?
MEDIUM
What is the role of omeprazole and esomeprazole in regulating the secretion of gastric juice?