A small viral peptide can insert its 6 amino acids (represented as a barrel) into the lipid bilayer as depicted in the figure given below. The table depicts the different properties of amino acids. Properties Polar and uncharged Polar and charged Non-polar and hydrophobic Amino acids Gly Asp Ala Ser Glu Val Thr Lys Leu Cys Arg Ile Asn His Pro Gln - Met Tyr - Phe - - Trp

- Ala - Leu - Ile - Leu - Leu - Ala - COOH

- Glu - Asp - Glu - Glu - Glu - Asp - COOH

- Met - Gln - Asp - Asn - Gly - Asp - COOH

- Lys - Arg - Arg - Arg - Lys - Arg - COOH

Match the following (a) Inhibitor of catalytic activity (i) Ricin (b) Possess peptide bonds (ii) Malonate (c) Cell wall material in fungi (iii) Chitin (d) Secondary metabolite (iv) Collagen Choose the correct option from the following

(a)-(ii), (b)-(iv), (c)-(iii), (d)-(i)

(a)-(iii), (b)-(i), (c)-(iv), (d)-(ii)

(a)-(iii), (b)-(iv), (c)-(i), (d)-(ii)

(a)-(ii), (b)-(iii), (c)-(i), (d)-(iv)

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Amino acids, as the name suggests, have both an amino group and a carboxyl group in their structure. In addition, all naturally occurring amino acids (those which are found in proteins) are called L-amino acids. From this, can you guess from which compound can the simplest amino acid be made

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Important Questions on Biomolecules

EASY

Biology>Cell : Structure and Functions>Biomolecules>Proteins

How many different proteins consisting of 100 amino acids can be formed from 20 different amino acids?

MEDIUM

Biology>Cell : Structure and Functions>Biomolecules>Proteins

Protein is very essential for the growth, development and maintenance of living systems. Proteins are natural polymer of

α -

amino acids. A definite sequence of amino acids form a specific protein. Two or more than two amino acids bind to give peptide bond. Proteins are polypeptide, which loses its biological activity by physical or chemical changes.
Explain essential and non-essential amino acid with example.

HARD

Biology>Cell : Structure and Functions>Biomolecules>Proteins

Three given polypeptides

(P, Q

and

R)

, of same size and same

pI (7.2)

, have a single aspartic acid in each of them. In polypeptide

P

, the aspartic acid residue is on the surface. In polypeptide

Q

, it is surrounded by negatively charged residues, whereas in polypeptide

R

it is deeply buried in a hydrophobic core.

pKa

of the side chain carboxylate of free (in solution) aspartic acid is

3.65

. The polypeptides are in a buffer of

pH

7.4

. The change in

pKa

of the aspartic acid side chain carboxylate in the polypeptides

P, Q

and

R

is likely to

MEDIUM

Biology>Cell : Structure and Functions>Biomolecules>Proteins

Which of the following amino acids is NOT involved in gluconeogenesis?

MEDIUM

Biology>Cell : Structure and Functions>Biomolecules>Proteins

Choose the CORRECT combination of statements given below related to cysteine residue in proteins.

i. Cysteine can be linked to tyrosine by S-O bond.

ii. Cysteine can be linked to another cysteine by S-S bond.

iii. Cysteine can complex with

{Z n}^{2 +} .

iv. Cysteine can be linked to methionine by S-S bond

HARD

Biology>Cell : Structure and Functions>Biomolecules>Proteins

The activity of a certain protein is dependent on its phosphorylation. A mutation in its gene changed a single amino acid which affected the function of the molecule. Which amino acid change is most likely to account for this observation?

HARD

Biology>Cell : Structure and Functions>Biomolecules>Proteins

A small viral peptide can insert its $6$ amino acids (represented as a barrel) into the lipid bilayer as depicted in the figure given below. Question Image

The table depicts the different properties of amino acids.

	Properties
	Polar and uncharged	Polar and charged	Non-polar and hydrophobic
Amino acids	Gly	Asp	Ala
	Ser	Glu	Val
	Thr	Lys	Leu
	Cys	Arg	Ile
	Asn	His	Pro
	Gln	-	Met
	Tyr	-	Phe
	-	-	Trp

EASY

Biology>Cell : Structure and Functions>Biomolecules>Proteins

Identify the basic amino acid from the following.

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Biology>Cell : Structure and Functions>Biomolecules>Proteins

Which one of the pairs of amino acids contains two chiral centres?

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Biology>Cell : Structure and Functions>Biomolecules>Proteins

Which one of the following amino acids is least likely to be in the core of a protein

?

HARD

Biology>Cell : Structure and Functions>Biomolecules>Proteins

Which one of the following techniques is used for the detection of proteins?

EASY

Biology>Cell : Structure and Functions>Biomolecules>Proteins

Identify the statement which is incorrect.

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Biology>Cell : Structure and Functions>Biomolecules>Proteins

Which one of the following is the most abundant protein in the animals?

EASY

Biology>Cell : Structure and Functions>Biomolecules>Proteins

Which of the following is the least likely to be involved in stabilizing the three-dimensional folding of most proteins?

MEDIUM

Biology>Cell : Structure and Functions>Biomolecules>Proteins

Match the following

(a)	Inhibitor of catalytic activity	(i)	Ricin
(b)	Possess peptide bonds	(ii)	Malonate
(c)	Cell wall material in fungi	(iii)	Chitin
(d)	Secondary metabolite	(iv)	Collagen

Choose the correct option from the following

EASY

Biology>Cell : Structure and Functions>Biomolecules>Proteins

Amino acid analysis of two globular protein samples yielded identical composition per mole. Which one of the following characteristics is necessarily identical for the two proteins

?

MEDIUM

Biology>Cell : Structure and Functions>Biomolecules>Proteins

In primary structure of protein, the protein thread showed helix with four amino acids

S - C - Y - E

and a naphthalene structure in amino acid

Y .

In such condition what will be the direction of helix and what are the positions of amino acids

MEDIUM

Biology>Cell : Structure and Functions>Biomolecules>Proteins

If the acidic, basic and hydrophobic residues of proteins are considered to be red, green and blue in colour, respectively, then a globular protein in aqueous solution would have

EASY

Biology>Cell : Structure and Functions>Biomolecules>Proteins

Among the following, identify the zwitterionic form

EASY

Biology>Cell : Structure and Functions>Biomolecules>Proteins

Which one of the following statements is wrong?

Amino acids, as the name suggests, have both an amino group and a carboxyl group in their structure. In addition, all naturally occurring amino acids (those which are found in proteins) are called L-amino acids. From this, can you guess from which compound can the simplest amino acid be made

Important Questions on Biomolecules

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