Translation

IMPORTANT

Translation: Overview

This topic covers concepts such as Translation of mRNA to Protein, Activation of Amino Acids, Aminoacylation of tRNA, Initiation of Protein Synthesis, Elongation of Protein Synthesis, Termination of Protein Synthesis and Untranslated Regions of mRNA.

Important Questions on Translation

HARD
IMPORTANT

In mRNA, the untranslated region are present only at 5' end.

EASY
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The formation of a peptide bond is catalysed by the enzyme _____. (peptidyl transferase/ribozyme)

MEDIUM
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What are polysomes or polyribosomes? 

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The triplet on the coding strand of DNA is ATG. What would be the required anticodon on the corresponding tRNA during translation?

MEDIUM
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Which of the following is not correct about translation?

EASY
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Which one of the following pairs is correctly matched?

MEDIUM
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In protein synthesis first amino acid in polypeptide chain is normally methionine. But if methionine is not required in polypeptide chain it is separated from polypeptide chain by :-

MEDIUM
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During initiation of translation in prokaryotes, a GTP molecule is required in:-

MEDIUM
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Select the odd one out w.r.t. Shine Dalgarno sequence.

MEDIUM
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Assertion : Peptidyl transfer site is jointly contributed by the two ribosomal subunits.

Reason : The enzyme peptidyl transferase is contributed by both 23S and 16S ribosomal subunits.

EASY
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In the protein synthesis, tRNA carrying the amino acid enters from which site of ribosome?

MEDIUM
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What would happen if in a gene encoding a polypeptide of 50 amino acids 25th (UAC) is mutated to UAA?

EASY
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Protein synthesis in an animal cell takes place

EASY
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What would happen if in a gene encoding a polypeptide of 50 amino acids, 25th codon (UAU) is mutated to UAA?

MEDIUM
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During translation initiation in prokaryotes, a GTP molecule is necessary for which of the following?

HARD
IMPORTANT

Gene and cistron words are sometimes used synonymously because

EASY
IMPORTANT

Anticodon is an unpaired triplet of bases in an exposed position of

EASY
IMPORTANT

Which is not involved in protein synthesis?