Taxol

Explain the discovery of taxol.

Which of the following is an anticancer drug?

Explain the synthesis of taxol from its precursor using auxiliaries.

Paclitaxel (Taxol) is an anticancer drug that can be extracted from the bark of Pacific yew tree (Taxus brevifolia) or produced semi-synthetically using extracts from the leaves of European yew trees (Taxus baccata). Since $1994$ the total synthesis of Taxol has been reported by several research groups in different countries. Suggest why total synthesis is not used for producing Taxol on an industrial scale?

Paclitaxel (Taxol) is an anticancer drug that can be extracted from the bark of Pacific yew tree (Taxus brevifolia) or produced semi-synthetically using extracts from the leaves of European yew trees (Taxus baccata). Discuss the advantages and disadvantages of extraction and semi-synthetic production of Taxol.

Paclitaxel (Taxol) is an anticancer drug that can be extracted from the bark of Pacific yew tree (Taxus brevifolia) or produced semi-synthetically using extracts from the leaves of European yew trees (Taxus baccata). State what is meant by the term semi-synthetic?

Cotyledons are also called-